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Alternatively, the nucleic acids on said microarray are selected from the group consisting, or consisting essentially, of the genes from Table VI. Ling, MH, Albrecht, J Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. Markers and methods for assessing and treating Crohn's and related disorders. Specific microarrays comprising these genes are contemplated as part of the invention.

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As discussed above an important aspect of the present invention is a method of obtaining an expression profile, using the microarray compositions of the invention, of a subject that has or is about to undergo therapy based on 20 IMPDH inhibition. The references cited herein throughout, to the extent that they provide exemplary procedural or other details supplementary to those set forth herein, are all specifically incorporated herein by reference.

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After hybridization, the microarray is washed to remove nonhybridized nucleic acids, and complex formation between the hybridizable array elements and the target polynucleotides is detected. And yet this crisis is indeed being wasted, and in this Budget, too. The method of claim 42, wherein said biological sample is a blood sample, a tissue biopsy, or a tumor cell isolated from a tumor biopsy.


Monitoring these patterns of gene expression changes are also likely to be predictive of a beneficial outcome with other unknown IMPDH pathway inhibitors. Nucleotide array containing polynucleotide probes complementary to, or fragments of, cynomolgus monkey genes and the use thereof.

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Have your say at Andrew's blog But the Rudd Government is instead punishing the responsible and careful.

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